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(R) -PROTAC CDK9 ligand-1

(R) -PROTAC CDK9 ligand-1 (Compound 19.4) is a CDK9-targeting degrader that can be used to synthesize PROTAC with antitumor activity[1].

Product Specifications

CAS Number

[2411021-95-7]

UNSPSC

12352005

Target

CDK; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PROTAC

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-protac-cdk9-ligand-1.html

Solubility

10 mM in DMSO

Smiles

CC(C1=C2N=C(N[C@@H](CO)CC)C=C(NCC3=CC=C(N)C=C3)N2N=C1)C

Molecular Formula

C20H28N6O

Molecular Weight

368.48

References & Citations

[1]Xiaohua Chen, et al. Preparation of degradation agents for cyclin dependent kinase useful for the treatment of cancer. Patent CN110835345A.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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