(R)-PROTAC CDK9 ligand-1
Product Specifications
UNSPSC Description
(R)-PROTAC CDK9 ligand-1 (Compound 19.4) is a CDK9-targeting degrader that can be used to synthesize PROTAC with antitumor activity[1].
Target Antigen
CDK; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-protac-cdk9-ligand-1.html
Solubility
10 mM in DMSO
Smiles
CC(C1=C2N=C(N[C@@H](CO)CC)C=C(NCC3=CC=C(N)C=C3)N2N=C1)C
Molecular Weight
368.48
References & Citations
[1]Xiaohua Chen, et al. Preparation of degradation agents for cyclin dependent kinase useful for the treatment of cancer. Patent CN110835345A.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115729A/R-PROTAC-CDK9-ligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115729A/
Clinical Information
No Development Reported
CAS Number
2411021-95-7
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