(R) -PROTAC CDK9 ligand-1
(R) -PROTAC CDK9 ligand-1 (Compound 19.4) is a CDK9-targeting degrader that can be used to synthesize PROTAC with antitumor activity[1].
Product Specifications
CAS Number
[2411021-95-7]
UNSPSC
12352005
Target
CDK; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-protac-cdk9-ligand-1.html
Solubility
10 mM in DMSO
Smiles
CC(C1=C2N=C(N[C@@H](CO)CC)C=C(NCC3=CC=C(N)C=C3)N2N=C1)C
Molecular Formula
C20H28N6O
Molecular Weight
368.48
References & Citations
[1]Xiaohua Chen, et al. Preparation of degradation agents for cyclin dependent kinase useful for the treatment of cancer. Patent CN110835345A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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