Antileishmanial agent-1
Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM) .
Product Specifications
CAS Number
[2454115-43-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-1.html
Solubility
10 mM in DMSO
Smiles
OC(C1=CC=C(Br)C=C1)C2=CN(C3=CC=C(Br)C=C3)N=N2
Molecular Formula
C15H11Br2N3O
Molecular Weight
409.08
References & Citations
[1]Almeida-Souza F, et al. Nitric Oxide Induction in Peritoneal Macrophages by a 1,2,3-Triazole Derivative Improves Its Efficacy upon Leishmania amazonensisIn Vitro Infection. J Med Chem. 2021 Sep 9;64 (17) :12691-12704.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
Curated Selection
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