Antileishmanial agent-1

Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM) .

Product Specifications

CAS Number

[2454115-43-4]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antileishmanial-agent-1.html

Solubility

10 mM in DMSO

Smiles

OC(C1=CC=C(Br)C=C1)C2=CN(C3=CC=C(Br)C=C3)N=N2

Molecular Formula

C15H11Br2N3O

Molecular Weight

409.08

References & Citations

[1]Almeida-Souza F, et al. Nitric Oxide Induction in Peritoneal Macrophages by a 1,2,3-Triazole Derivative Improves Its Efficacy upon Leishmania amazonensisIn Vitro Infection. J Med Chem. 2021 Sep 9;64 (17) :12691-12704.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Leishmania

Curated Selection

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