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Antiallergic agent-1

Antiallergic agent-1, a Src-family kinase inhibitor, may serve as a new valuable lead compound for future antiallergic agent discovery. Antiallergic agent-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2839159-12-3

UNSPSC

12352005

Target

Src

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/antiallergic-agent-1.html

Solubility

10 mM in DMSO

Smiles

CN1N=CC(C2=CN=C(C(C#CC3=CC(C(NC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)=CC=C3C)=C2)N)=C1

Molecular Formula

C27H19F6N5O

Molecular Weight

543.46

References & Citations

[1]Xie Z, et al. Discovery of Potent Antiallergic Agents Based on an o-Aminopyridinyl Alkynyl Scaffold. J Med Chem. 2021 Sep 23;64 (18) :13588-13603.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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