Heme Oxygenase-1-IN-2
Heme Oxygenase-1-IN-2 is a novel heme oxygenase-1 inhibitor (IC50 = 0.95 μM) with potent in vitro antiproliferative activity.
Product Specifications
CAS Number
2839158-50-6
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/heme-oxygenase-1-in-2.html
Solubility
10 mM in DMSO
Smiles
CN(C(C1=CC=C(C=C1)Cl)C2=CC=CC=C2)C(CN3C=CN=C3)=O
Molecular Formula
C19H18ClN3O
Molecular Weight
339.82
References & Citations
[1]Fallica AN, et al. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity. J Med Chem. 2021 Sep 23;64 (18) :13373-13393.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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