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Heme Oxygenase-1-IN-2

Heme Oxygenase-1-IN-2 is a novel heme oxygenase-1 inhibitor (IC50 = 0.95 μM) with potent in vitro antiproliferative activity.

Product Specifications

CAS Number

2839158-50-6

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/heme-oxygenase-1-in-2.html

Solubility

10 mM in DMSO

Smiles

CN(C(C1=CC=C(C=C1)Cl)C2=CC=CC=C2)C(CN3C=CN=C3)=O

Molecular Formula

C19H18ClN3O

Molecular Weight

339.82

References & Citations

[1]Fallica AN, et al. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity. J Med Chem. 2021 Sep 23;64 (18) :13373-13393.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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