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Neladenoson dalanate (hydrochloride)

Neladenoson dalanate (Neladenoson bialanate; BAY-1067197) hydrochloride is a orally active agonist precursor of partial Adenosine A1 Receptor. Neladenoson dalanate hydrochloride has a good pharmacokinetic and safety profile, can be used for the chronic heart diseases[1].

Product Specifications

CAS Number

1239235-25-6

Product Name Alternative

Neladenoson bialanate (hydrochloride) ; BAY-1067197 (hydrochloride)

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/neladenoson-dalanate-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](C(OCCOC1=CC=C(C2=C(C#N)C(SCC3=CSC(C4=CC=C(Cl)C=C4)=N3)=NC(N5CCCC5)=C2C#N)C=C1)=O)NC([C@H](C)N)=O.[H]Cl

Molecular Formula

C35H35Cl2N7O4S2

Molecular Weight

752.73

References & Citations

[1]Meibom D, et al. Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A1 Receptor Agonist for the Chronic Treatment of Heart Diseases. ChemMedChem. 2017 May 22;12 (10) :728-737.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

Adenosine A1 receptor (A1R)

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