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GB111-NH2

GB111-NH2 is a cysteine cathepsin inhibitor and can be used in cancer research[1].

Product Specifications

CAS Number

[956479-18-8]

UNSPSC

12352005

Target

Cathepsin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gb111-nh2.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)CCCCN)=O)C3=C(C)C=CC=C3C

Molecular Formula

C33H39N3O6

Molecular Weight

573.68

References & Citations

[1]Salpeter SJ, et al. A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression. Oncogene. 2015 Dec 10;34 (50) :6066-78.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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