Y02224
Y02224 is a potent BRD4 inhibitor and exhibits reasonable antiproliferative effect on leukemia cells.Y02224 has the potential for CRPC research[1].
Product Specifications
CAS Number
1853988-48-3
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/y02224.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C3=CC=C2)C(N1CC)=CC=C3NS(C4=C(C=CC(Br)=C4)OC)(=O)=O
Molecular Formula
C20H17BrN2O4S
Molecular Weight
461.33
References & Citations
[1]Maofeng Zhang, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC) . J Med Chem. 2018 Apr 12;61 (7) :3037-3058.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb3130986-01 48 Tests
Human cANCA (Cytoplasmic anti-neutrophil cytoplasmic antibody) ELISA Kit
Sign In for Pricing
View Details orb3130986-02 96 Tests
Human cANCA (Cytoplasmic anti-neutrophil cytoplasmic antibody) ELISA Kit
Sign In for Pricing
View Details 
