Indomethacin heptyl ester
Indomethacin heptyl ester is a selective COX-2 inhibitor with IC50 of 0.04 μM, exhibits anti-inflammatory activity[1].
Product Specifications
CAS Number
[282728-47-6]
UNSPSC
12352005
Hazard Statement
H225, H319, H336
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/indomethacin-heptyl-ester.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C=C1)C(N2C3=C(C(CC(OCCCCCCC)=O)=C2C)C=C(OC)C=C3)=O
Molecular Formula
C26H30ClNO4
Molecular Weight
455.97
Precautions
H225, H319, H336
References & Citations
[1]A S Kalgutkar, et al. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. J Med Chem. 2000 Jul 27;43 (15) :2860-70.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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