CGA-JK3

CGA-JK3 is CGA-JK3 is an ATP-competitive inhibitor of IKKβ-catalyzed kinase activity. CGA-JK3 inhibits IκBα phosphorylation in LPS (HY-D1056) - induced RAW 264.7 cells[1].

Product Specifications

CAS Number

[1621626-06-9]

UNSPSC

12352005

Target

IKK

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cga-jk3.html

Solubility

10 mM in DMSO

Smiles

O=C(/C=C/C1=CC=C(C(O)=C1)O)NC2CCCCC2

Molecular Formula

C15H19NO3

Molecular Weight

261.32

References & Citations

[1]Choi JH, et al. Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process. Sci Rep. 2017;7:41180. Published 2017 Feb 1.