CGA-JK3
CGA-JK3 is CGA-JK3 is an ATP-competitive inhibitor of IKKβ-catalyzed kinase activity. CGA-JK3 inhibits IκBα phosphorylation in LPS (HY-D1056) - induced RAW 264.7 cells[1].
Product Specifications
CAS Number
[1621626-06-9]
UNSPSC
12352005
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cga-jk3.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=C(C(O)=C1)O)NC2CCCCC2
Molecular Formula
C15H19NO3
Molecular Weight
261.32
References & Citations
[1]Choi JH, et al. Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process. Sci Rep. 2017;7:41180. Published 2017 Feb 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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