Jacareubin
Jacareubin is a xanthone compound that can be isolated from Calophyllum brasiliense. Jacareubin has antibacterial, antioxidant, gastroprotective properties, and also has certain cancer cell toxicity, which can be used in cancer research[1].
Product Specifications
CAS Number
[3811-29-8]
UNSPSC
12352005
Target
Bacterial; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jacareubin.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C=C3C(C=CC(C)(O3)C)=C2O)OC4=C1C=CC(O)=C4O
Molecular Formula
C18H14O6
Molecular Weight
326.30
References & Citations
[1]W R García-Niño, et al. Cytogenetic effects of Jacareubin from Calophyllum brasiliense on human peripheral blood mononucleated cells in vitro and on mouse polychromatic erythrocytes in vivo. Toxicol Appl Pharmacol. 2017 Nov 15;335:6-15.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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