Lenperone (hydrochloride)

Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research[1][2].

Product Specifications

CAS Number

[24677-86-9]

Product Name Alternative

AHR 2277

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lenperone-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(CCCN1CCC(CC1)C(C2=CC=C(C=C2)F)=O)C3=CC=C(C=C3)F.Cl

Molecular Formula

C22H24ClF2NO2

Molecular Weight

407.88

References & Citations

[1]Johnson SE, et al. Effect of lenperone hydrochloride on gastroesophageal sphincter pressure in healthy dogs. Can J Vet Res. 1989 Apr;53 (2) :248-50.|[2]Costall B, Naylor RJ. Mesolimbic involvement with behavioural effects indicating antipsychotic activity. Eur J Pharmacol. 1974 Jun;27 (1) :46-58.