Taprostene

Taprostene (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2) . Taprostene exhibits endothelium and myocardial protecting actions after acute myocardial ischemia and reperfusion in cats. Taprostene enhances cytoprotective actions, while minimizing unwanted hemodynamic effects[1].

Product Specifications

CAS Number

[108945-35-3]

Product Name Alternative

CG-4203

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/taprostene.html

Purity

98.1

Solubility

10 mM in DMSO

Smiles

O[C@@H](C1CCCCC1)/C=C/[C@@H]2[C@]3([H])[C@@](C[C@H]2O)([H])O/C(C3)=C\C4=CC(C(O)=O)=CC=C4

Molecular Formula

C24H30O5

Molecular Weight

398.49

References & Citations

[1]G Johnson 3rd, et al. Endothelium and myocardial protecting actions of Taprostene, a stable prostacyclin analogue, after acute myocardial ischemia and reperfusion in cats. Circ Res. 1990 May;66 (5) :1362-70.