TMC-205

TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].

Product Specifications

CAS Number

[403646-00-4]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tmc-205.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CNC2=C1C=CC(/C=C/C(C)=C)=C2)O

Molecular Formula

C14H13NO2

Molecular Weight

227.26

References & Citations

[1]Gao Y, et al. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014;5 (8) :863-867. Published 2014 Jun 23.