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Protokylol

Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator[1].

Product Specifications

CAS Number

[136-70-9]

Product Name Alternative

Caytine; JB-251

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Adrenergic Receptor; TRP Channel

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/protokylol.html

Solubility

10 mM in DMSO

Smiles

CC(CC1=CC2=C(C=C1)OCO2)NCC(C3=CC=C(C(O)=C3)O)O

Molecular Formula

C18H21NO5

Molecular Weight

331.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Corina Andrei, et al. In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity. Pharmaceutics. 2022 Nov 22;14 (12) :2563.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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