Protokylol
Protokylol (Caytine; JB-251) is a beta-adrenergic receptor agonist and TRPV1 agonist. Protokylol is used as a bronchodilator[1].
Product Specifications
CAS Number
[136-70-9]
Product Name Alternative
Caytine; JB-251
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor; TRP Channel
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/protokylol.html
Solubility
10 mM in DMSO
Smiles
CC(CC1=CC2=C(C=C1)OCO2)NCC(C3=CC=C(C(O)=C3)O)O
Molecular Formula
C18H21NO5
Molecular Weight
331.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Corina Andrei, et al. In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity. Pharmaceutics. 2022 Nov 22;14 (12) :2563.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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