U27391
U27391 is a metalloproteinase inhibitor. U27391 inhibits rhIL-1β Induced proteoglycan loss[1].
Product Specifications
CAS Number
106314-87-8
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/u27391.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@@H](NC(C(CC(C)C)CC(NO)=O)=O)CC(C)C)=O)CC1=CC=CC=C1)N
Molecular Formula
C23H36N4O5
Molecular Weight
448.56
References & Citations
[1]Seed MP, et al. Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391. Ann Rheum Dis. 1993 Jan;52 (1) :37-43.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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