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Asobamast

Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED50=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments[1].

Product Specifications

CAS Number

[104777-03-9]

UNSPSC

12352005

Target

TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/asobamast.html

Solubility

10 mM in DMSO

Smiles

O=C(C(OCCOCC)=O)NC1=NC(C2=CC(C)=NO2)=CS1

Molecular Formula

C13H15N3O5S

Molecular Weight

325.34

References & Citations

[1]D Chiarino, et al. N- (4-Isoxazolylthiazol-2-yl) oxamic acid derivatives as potent orally active antianaphylactic agents. J Med Chem. 1991 Feb;34 (2) :600-5.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-114538/Asobamast-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-114538/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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