AT-1002

AT-1002, a 6-mer synthetic peptide[1], is a tight junction regulator and absorption enhancer[2].

Product Specifications

CAS Number

[835872-35-0]

UNSPSC

12352005

Target

Gap Junction Protein

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/AT-1002.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CS)C(N[C@@H]([C@H](CC)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O

Molecular Formula

C32H53N9O7S

Molecular Weight

707.88

References & Citations

[1]Li M, et al. Structure-activity relationship studies of permeability modulating peptide AT-1002. Bioorg Med Chem Lett. 2008 Aug 15;18 (16) :4584-6.|[2]Gopalakrishnan S, et al. Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer. Int J Pharm. 2009 Jan 5;365 (1-2) :121-30.