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DSP-0565

Product Specifications

UNSPSC Description

DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin[1].

Target Antigen

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dsp-0565.html

Solubility

10 mM in DMSO

Smiles

O=C(N)CC1=CC=CC=C1C2=CC=CC=C2F

Molecular Weight

229.25

References & Citations

[1]Tanaka T, et al. Identification of 2-(2'-fluoro-[1,1'-biphenyl]-2-yl)acetamide as a Sodium Valproate-like broad spectrum anti-epileptic drug candidate. Bioorg Med Chem Lett. 2019 Jan 15;29(2):138-142.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-114300/DSP-0565-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-114300/

Clinical Information

Phase 1

CAS Number

1226855-28-2

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