DSP-0565
DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin[1].
Product Specifications
CAS Number
[1226855-28-2]
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dsp-0565.html
Solubility
10 mM in DMSO
Smiles
O=C(N)CC1=CC=CC=C1C2=CC=CC=C2F
Molecular Formula
C14H12FNO
Molecular Weight
229.25
References & Citations
[1]Tanaka T, et al. Identification of 2- (2'-fluoro-[1,1'-biphenyl]-2-yl) acetamide as a Sodium Valproate-like broad spectrum anti-epileptic drug candidate. Bioorg Med Chem Lett. 2019 Jan 15;29 (2) :138-142.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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