DSP-0565

DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin[1].

Product Specifications

CAS Number

[1226855-28-2]

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dsp-0565.html

Solubility

10 mM in DMSO

Smiles

O=C(N)CC1=CC=CC=C1C2=CC=CC=C2F

Molecular Formula

C14H12FNO

Molecular Weight

229.25

References & Citations

[1]Tanaka T, et al. Identification of 2- (2'-fluoro-[1,1'-biphenyl]-2-yl) acetamide as a Sodium Valproate-like broad spectrum anti-epileptic drug candidate. Bioorg Med Chem Lett. 2019 Jan 15;29 (2) :138-142.