Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Acetyl coenzyme A

Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis[1][2][3][4].

Product Specifications

CAS Number

72-89-9

Product Name Alternative

Acetyl-CoA

UNSPSC

12352005

Target

Autophagy; Endogenous Metabolite; Oxidative Phosphorylation

Type

Reference compound

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/acetyl-coenzyme-a.html

Solubility

10 mM in DMSO

Smiles

CC(SCCNC(CCNC([C@H](O)C(C)(C)COP(OP(O)(OC[C@H]1O[C@@H](N(C=N2)C3=C2C(N)=NC=N3)[C@H](O)[C@@H]1OP(O)(O)=O)=O)(O)=O)=O)=O)=O

Molecular Formula

C23H38N7O17P3S

Molecular Weight

809.57

References & Citations

[1]Choudhary C, et al. The growing landscape of lysine acetylation links metabolism and cell signalling. Nat Rev Mol Cell Biol. 2014 Aug;15 (8) :536-50. |[2]Mariño G, et al. Regulation of autophagy by cytosolic acetyl-coenzyme A. Mol Cell. 2014 Mar 6;53 (5) :710-25. |[3]Zhu H, et al. Cardiac autophagy is a maladaptive response to hemodynamic stress. J Clin Invest. 2007 Jul;117 (7) :1782-93. |[4]Pietrocola F, et al. Acetyl coenzyme A: a central metabolite and second messenger. Cell Metab. 2015 Jun 2;21 (6) :805-21.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

5b-Dihydro Progesterone
TRC-D449280-5G 5 g

5b-Dihydro Progesterone

Sign In for Pricing
View Details
PRMT4 (CARM1) Human Gene Knockout Kit (CRISPR)
KN217483BN 1 Kit

PRMT4 (CARM1) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
CMTM1 Rabbit Polyclonal Antibody
TA371099 100 µL

CMTM1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Recombinant SARS-CoV-2 S-trimer (D614G, N439K) (His Tag)
PKSV030389-01 50 µg

Recombinant SARS-CoV-2 S-trimer (D614G, N439K) (His Tag)

Sign In for Pricing
View Details
Recombinant SARS-CoV-2 S-trimer (D614G, N439K) (His Tag)
PKSV030389-02 500 µg

Recombinant SARS-CoV-2 S-trimer (D614G, N439K) (His Tag)

Sign In for Pricing
View Details
D-Allocystathionine
TRC-A546125-5MG 5 mg

D-Allocystathionine

Sign In for Pricing
View Details