Eckol

Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects[1][2][3][4].

Product Specifications

CAS Number

[88798-74-7]

Product Name Alternative

BE003

UNSPSC

12352005

Target

Influenza Virus; Monoamine Oxidase

Type

Natural Products

Related Pathways

Anti-infection; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/eckol.html

Purity

98.95

Solubility

10 mM in DMSO

Smiles

OC1=C2C(OC3=C(O)C=C(O)C=C3O2)=C(OC4=CC(O)=CC(O)=C4)C(O)=C1

Molecular Formula

C18H12O9

Molecular Weight

372.28

References & Citations

[1]Jung HA, et al. Evaluation of the inhibitory effects of eckol and dieckol isolated from edible brown alga Eisenia bicyclis on human monoamine oxidases A and B. Arch Pharm Res. 2017 Apr;40 (4) :480-491.|[2]Rengasamy KR, et al. Enhancing growth, phytochemical constituents and aphid resistance capacity in cabbage with foliar application of eckol--a biologically active phenolic molecule from brown seaweed. N Biotechnol. 2016 Mar 25;33 (2) :273-9.|[3]Han EJ, et al. Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice. Nutrients. 2020 May 9;12 (5) :1361.|[4]Besednova NN, et al. Antiviral Effects of Polyphenols from Marine Algae. Biomedicines. 2021 Feb 17;9 (2) :200.