CCR1 antagonist 6
CCR1 antagonist 6 (compound 16q) is a chemokine receptor 1 (CCR1) antagonist, with an IC50 of 3 nM[1].
Product Specifications
CAS Number
2436773-01-0
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/ccr1-antagonist-6.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CN=CC([C@@H](NC(C2=C(C)N(C3=CC=C(Cl)C=C3)N=C2)=O)CCC)=C1)(C)=O
Molecular Formula
C21H23ClN4O3S
Molecular Weight
446.95
References & Citations
[1]Harcken C, et al. Discovery and optimization of pyrazole amides as antagonists of CCR1. Bioorg Med Chem Lett. 2019 Feb 1;29 (3) :435-440.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR1
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