Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TGFβRI-IN-1

TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .

Product Specifications

CAS Number

1950628-94-0

UNSPSC

12352005

Target

TGF-β Receptor

Type

Reference compound

Related Pathways

TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

CC(NC1=NC=CC(C(N2)=C(C3=NC=C(OC([2H])([2H])[2H])C=C3)C4=C2C=CC=N4)=C1)=O

Molecular Formula

C20H14D3N5O2

Molecular Weight

362.40

References & Citations

[1]Yong Zhang, et al. Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents. ACS Med. Chem. Lett.20189111117-1122.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

L-Alanine-13C3
TRC-A481504-25MG 25 mg

L-Alanine-13C3

Sign In for Pricing
View Details
Recombinant Human Interleukin-18/IL-18 Protein (GST Tag)
PKSH030306 50 µg

Recombinant Human Interleukin-18/IL-18 Protein (GST Tag)

Sign In for Pricing
View Details
Tissue FFPE Sections, Thyroid gland
CS710210 5x 5 µm

Tissue FFPE Sections, Thyroid gland

Sign In for Pricing
View Details
Polystyrene A HMBA
HA16020014.5G 5 g

Polystyrene A HMBA

Sign In for Pricing
View Details
Aquaporin 8 (AQP8) Mouse Monoclonal Antibody [Clone ID: OTI1C10]
CF810773 100 µg

Aquaporin 8 (AQP8) Mouse Monoclonal Antibody [Clone ID: OTI1C10]

Sign In for Pricing
View Details
Recombinant Human Ribonuclease A/RNASE1 Protein (His Tag)
PKSH033004-01 10 µg

Recombinant Human Ribonuclease A/RNASE1 Protein (His Tag)

Sign In for Pricing
View Details