KRAS G12C inhibitor 5

[2158297-63-1]

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/KRAS_G12C_inhibitor_5.html

10 mM in DMSO

N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1

C32H37N7O2

551.68

[1]John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.

Room temperature

Reference compound1

No Development Reported

K-Ras