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KRAS G12C inhibitor 5

KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

Product Specifications

CAS Number

[2158297-63-1]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/KRAS_G12C_inhibitor_5.html

Solubility

10 mM in DMSO

Smiles

N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1

Molecular Formula

C32H37N7O2

Molecular Weight

551.68

References & Citations

[1]John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

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