Kuguaglycoside C
Product Specifications
UNSPSC Description
Kuguaglycoside C is a triterpene glycoside that can be isolated from the leaves of Momordica charantia. Kuguaglycoside C induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF)[1].
Target Antigen
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kuguaglycoside-c.html
Solubility
10 mM in DMSO
Smiles
C=C(C)/C=C/C[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CC2)(C)[C@]([C@]2(C=O)[C@@](CC[C@H](O)C3(C)C)([H])C3=C4)([H])[C@H]4O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Molecular Weight
616.83
References & Citations
[1]Tabata K, et al. Kuguaglycoside C, a constituent of Momordica charantia, induces caspase-independent cell death of neuroblastoma cells. Cancer Sci. 2012 Dec;103(12):2153-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113915/Kuguaglycoside-C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113915/
Clinical Information
No Development Reported
CAS Number
1041631-93-9
Curated Selection
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