Desmethylcitalopram (hydrochloride)

Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203) . Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].

Product Specifications

CAS Number

[97743-99-2]

Product Name Alternative

DCIT (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/desmethylcitalopram-hydrochloride.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CNCCCC1(OCC2=CC(C#N)=CC=C21)C3=CC=C(C=C3)F.Cl

Molecular Formula

C19H20ClFN2O

Molecular Weight

346.83

Precautions

H302

References & Citations

[1]von Moltke LL, et aI. Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects. Biol Psychiatry. 1999 Sep 15;46 (6) :839-49.