A-940894

A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4) . A-940894 exhibits with anti-inflammatory properties[1].

Product Specifications

CAS Number

[1027330-82-0]

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/a-940894.html

Solubility

10 mM in DMSO

Smiles

NC1=NC(N2CCNCC2)=C3CCCC4=CC=CC=C4C3=N1

Molecular Formula

C17H21N5

Molecular Weight

295.38

References & Citations

[1]M I Strakhova, et al. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. Br J Pharmacol. 2009 May;157 (1) :44-54.