A-940894
A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4) . A-940894 exhibits with anti-inflammatory properties[1].
Product Specifications
CAS Number
1027330-82-0
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a-940894.html
Solubility
10 mM in DMSO
Smiles
NC1=NC(N2CCNCC2)=C3CCCC4=CC=CC=C4C3=N1
Molecular Formula
C17H21N5
Molecular Weight
295.38
References & Citations
[1]M I Strakhova, et al. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. Br J Pharmacol. 2009 May;157 (1) :44-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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