CP-67804
CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent[1].
Product Specifications
CAS Number
103978-08-1
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cp-67804.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(CC)C2=C(C=C(F)C(C3=CC=C(O)C=C3)=C2F)C1=O)O
Molecular Formula
C18H13F2NO4
Molecular Weight
345.30
References & Citations
[1]Robinson MJ, et al. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991;266 (22) :14585-14592.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
Frequently Asked Questions
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