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CP-67804

CP-67804 is a quinolone derivative, is a topoisomerase II-targeted agent. CP-67804 effectively enhances DNA cleavage mediated by eukaryotic topoisomerase II. CP-67804 has potential as an antineoplastic agent[1].

Product Specifications

CAS Number

103978-08-1

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cp-67804.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(CC)C2=C(C=C(F)C(C3=CC=C(O)C=C3)=C2F)C1=O)O

Molecular Formula

C18H13F2NO4

Molecular Weight

345.30

References & Citations

[1]Robinson MJ, et al. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991;266 (22) :14585-14592.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Topo II

Frequently Asked Questions

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