Temafloxacin (hydrochloride)

Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections[1][2].

Product Specifications

CAS Number

[105784-61-0]

Product Name Alternative

TMFX (hydrochloride) ; TA-167; A-62254

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H332-H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/temafloxacin-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C2=CC=C(F)C=C2F)C3=C(C=C(F)C(N4CC(C)NCC4)=C3)C1=O)O.Cl

Molecular Formula

C21H19ClF3N3O3

Molecular Weight

453.84

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Hardy DJ, et al. Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones. Antimicrob Agents Chemother. 1987 Nov;31 (11) :1768-74.|[2]Pankey GA. Temafloxacin: an overview. Am J Med. 1991 Dec 30;91 (6A) :166S-172S.