Tie2 kinase inhibitor 2
Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 μM. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1].
Product Specifications
CAS Number
[1020412-97-8]
UNSPSC
12352005
Hazard Statement
H302
Target
Tie
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tie2-kinase-inhibitor-2.html
Purity
99.00
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC=C(CN(CC(N[C@H](C3CCCCC3)C)=O)C(OC4=CC=C(C)C=C4)=O)C=C2)=CN=C1)O
Molecular Formula
C31H35N3O5
Molecular Weight
529.63
Precautions
H302
References & Citations
[1]Jinqi Liu, et al. Identification and characterization of small-molecule inhibitors of Tie2 kinase. FEBS Lett. 2008 Mar 5;582 (5) :785-91.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Tie2
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal Calponin 1 Antibody (CNN1/4227R) [DyLight 594]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
Rabbit Monoclonal Calponin 1 Antibody (CNN1/4227R) [DyLight 594]
Uhrf2 (E3 Ubiquitin-Protein Ligase UHRF2, 632-, NIRF, Np95-like ring Finger Protein, Nuclear Protein 97, Nuclear Zinc Finger Protein Np97, Ubiquitin-like PHD and RING Finger Domain-Containing Protein 2, Ubiquitin-like-Containing PHD and RING Finger Domain
Uhrf2 (E3 Ubiquitin-Protein Ligase UHRF2, 632-, NIRF, Np95-like ring Finger Protein, Nuclear Protein 97, Nuclear Zinc Finger Protein Np97, Ubiquitin-like PHD and RING Finger Domain-Containing Protein 2, Ubiquitin-like-Containing PHD and RING Finger Domain