5 (S) 15 (S) -DiHETE

5 (S) 15 (S) -DiHETE is an “activated” intermediate, inhibits platelet aggregation with an IC50 of 1.3 μM. 5 (S) 15 (S) -DiHETE enhances the rate of either LXA4 or LXB4 biosynthesis[1].

Product Specifications

CAS Number

[82200-87-1]

UNSPSC

12352211

Hazard Statement

H225, H319

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/5-s-15-s-dihete.html

Concentration

297.20 μM * 250 μL in Ethanol

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CCCCC[C@H](O)/C=C/C=C\C/C=C\C=C\[C@@H](O)CCCC(O)=O

Molecular Formula

C20H32O4

Molecular Weight

336.47

Precautions

H225, H319

References & Citations

[1]Abigail R Green, et al. 5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1. Biochemistry. 2018 Dec 4;57 (48) :6726-6734.