5-HETE
Product Specifications
UNSPSC Description
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5-hete.html
Purity
96.0
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C=C\C(O)CCCC(O)=O
Molecular Weight
320.47
References & Citations
[1]J T O'Flaherty, et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. Am J Pathol. 1981 Jul;104(1):55-62.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113434B/5-HETE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113434B/5-HETE-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
71030-39-2
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