11-Dehydro-thromboxane B2

11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis[1][2].

Product Specifications

CAS Number

[67910-12-7]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/11-dehydro-thromboxane-b2.html

Concentration

1.36 mM * 100 μL in Methyl acetate

Purity

99.9

Solubility

DMSO : 1 mg/mL (ultrasonic; warming)

Smiles

O=C(O)CCC/C=C\C[C@@H]([C@@H](O)C1)[C@@H](/C=C/[C@@H](O)CCCCC)OC1=O

Molecular Formula

C20H32O6

Molecular Weight

368.46

Precautions

H302, H312, H332

References & Citations

[1]Simeone P, et al. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis. Ageing Res Rev. 2018 Dec;48:51-78. |[2]Lopez LR, et al. Platelet thromboxane (11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease. World J Diabetes. 2014 Apr 15;5 (2) :115-27.