Deoxycorticosterone-d8

Deoxycorticosterone-d8 is the deuterium labeled Deoxycorticosterone. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor[1][2].

Product Specifications

CAS Number

[55487-63-3]

UNSPSC

12352211

Hazard Statement

H351, H373

Target

Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Purity

97.77

Solubility

DMSO : ≥ 250mg/mL

Smiles

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C(C3)([2H])[2H])=C(C(=O)C(C4)([2H])[2H])[2H])(CC1)[H])[H])(CC[C@@]2(C(C(O)([2H])[2H])=O)[2H])[H]

Molecular Formula

C21H22D8O3

Molecular Weight

338.51

Precautions

H351, H373

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]KAGAWA CM, et al. Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt. Science. 1957 Nov 15;126 (3281) :1015-6.