L-Glyceric acid (sodium)

L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2) . L-Glyceric acid sodium excretion to distinguish PH1 from PH2[1][2].

Product Specifications

CAS Number

[146298-95-5]

UNSPSC

12352211

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-glyceric-acid-sodium.html

Purity

99.0

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O[Na])[C@@H](O)CO

Molecular Formula

C3H5NaO4

Molecular Weight

128.06

Precautions

H302, H312, H332

References & Citations

[1]Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16 (3) :191-8.|[2]Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18 (10) :986-91.