Uridine 5'-diphosphate

Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor[1].

Product Specifications

CAS Number

[58-98-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite; P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/uridine-5-diphosphate.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O[C@H]1N2C(NC(C=C2)=O)=O

Molecular Formula

C9H14N2O12P2

Molecular Weight

404.16

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Ashleigh S Paparella, et al. Clostridioides difficile TcdB Toxin Glucosylates Rho GTPase by an SNi Mechanism and Ion Pair Transition State. ACS Chem Biol. 2022 Sep 16;17 (9) :2507-2518. |[2]Besada P, et al. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J Med Chem. 2006 Sep 7;49 (18) :5532-43.