Aldosterone-d4

Aldosterone-d4 is the deuterium labeled Aldosterone. Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by t

Product Specifications

UNSPSC

12352211

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Concentration

274.37 μM * 1 mL in Acetonitrile

Purity

99.30

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@@]3([2H])[C@](O)([2H])C([2H])([2H])[C@]4(C=O)[C@@H](C(CO)=O)CC[C@@]4([H])[C@]3([H])CCC1=CC(CC2)=O

Molecular Formula

C21H24D4O5

Molecular Weight

364.47

Precautions

H302, H312, H332

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Nanba K, et al. Aging and Adrenal Aldosterone Production. Hypertension. 2018 Feb;71 (2) :218-223.; Cannavo A, et al. Aldosterone and Mineralocorticoid Receptor System in Cardiovascular Physiology and Pathophysiology. Oxid Med Cell Longev. 2018 Sep 19;2018:12