3-Hydroxykynurenine-13C3,15N
3-Hydroxykynurenine-13C3,15N (3-Hydroxy-DL-kynurenine-13C3,15N) is the 13C and 15N labeled 3-Hydroxykynurenine. 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis[2].
Product Specifications
CAS Number
2267306-16-9
Product Name Alternative
3-Hydroxy-DL-kynurenine-13C3,15N
UNSPSC
12352005
Target
Apoptosis; Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hydroxykynurenine-13c3-15n.html
Purity
98.74
Solubility
10 mM in DMSO
Smiles
O=C(C(C=CC=C1O)=C1N)[13CH2][13CH]([15NH2])[13C](O)=O
Molecular Formula
C7 13C3H12N 15NO4
Molecular Weight
228.18
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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