3- (3-Hydroxyphenyl) -3-hydroxypropanoic acid

3- (3-Hydroxyphenyl) -3-hydroxypropanoic acid is an endogenous metabolite present in Urine that can be used for the research of Autism[1][2].

Product Specifications

CAS Number

[3247-75-4]

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/3-_3-Hydroxyphenyl_-3-hydroxypropanoic_acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC(O)C1=CC=CC(O)=C1

Molecular Formula

C9H10O4

Molecular Weight

182.17

Precautions

H302, H312, H332

References & Citations

[1]Shaw W. Increased urinary excretion of a 3- (3-hydroxyphenyl) -3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of Clostridia spp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. Nutr Neurosci. 2010 Jun;13 (3) :135-43. |[2]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720.