Guanosine triphosphate-13C (dilithium)
Product Specifications
UNSPSC Description
Guanosine triphosphate-13C (GTP-13C) dilithium is 13C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
Target Antigen
DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog; SARS-CoV
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/guanosine-triphosphate-13c-dilithium.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(O)(O[Li])=O)(O[Li])=O)(O)=O)O[C@H]1N2[13CH]=NC3=C2N=C(N)NC3=O
Molecular Weight
536.04
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Abdo A Elfiky, et al. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113225S2/Guanosine-triphosphate-13C-dilithium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113225S2/
Clinical Information
No Development Reported
Curated Selection
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