Guanosine triphosphate
Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19[1].
Product Specifications
CAS Number
86-01-1
Product Name Alternative
GTP
UNSPSC
12352005
Target
DNA/RNA Synthesis; Endogenous Metabolite; Nucleoside Antimetabolite/Analog; SARS-CoV
Type
Oligonucleotides
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/guanosine-triphosphate.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Molecular Formula
C10H16N5O14P3
Molecular Weight
523.18
References & Citations
[1]Abdo A Elfiky, et al. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Isoform
Human Endogenous Metabolite
Citation 01
Acta Pharm Sin B. 2024 Apr;14 (4) :1864-1877.|Cancer Commun (Lond) . 2025 May 29.|J Mol Biol. 2024 Apr 15;436 (8) :168513.|Bioorg Med Chem. 2021 Jan 1;29:115899.|bioRxiv. 2024 Apr 24.
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