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Guanosine triphosphate

Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19[1].

Product Specifications

CAS Number

[86-01-1]

Product Name Alternative

GTP

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Nucleoside Antimetabolite/Analog; SARS-CoV

Type

Oligonucleotides

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/guanosine-triphosphate.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Molecular Formula

C10H16N5O14P3

Molecular Weight

523.18

References & Citations

[1]Abdo A Elfiky, et al. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

Phase 3

Isoform

Human Endogenous Metabolite

Citation 01

Acta Pharm Sin B. 2024 Apr;14 (4) :1864-1877.|Cancer Commun (Lond) . 2025 May 29.|J Mol Biol. 2024 Apr 15;436 (8) :168513.|Bioorg Med Chem. 2021 Jan 1;29:115899.|bioRxiv. 2024 Apr 24.
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