Asymmetric dimethylarginine (dihydrochloride)

Asymmetric dimethylarginine dihydrochloride is an endogenous NO synthase inhibitor that reduces NO production, which contributes to endothelial dysfunction and cardiovascular disease[1].

Product Specifications

CAS Number

[220805-22-1]

Product Name Alternative

NG, NG-Dimethylarginine (dihydrochloride)

UNSPSC

12352211

Hazard Statement

H315-H319

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/asymmetric-dimethylarginine-dihydrochloride.html

Purity

99.99

Solubility

H2O : 100 mg/mL (ultrasonic; warming)

Smiles

[H]Cl.[H]Cl.CN(C)C(NCCC[C@H](N)C(O)=O)=N

Molecular Formula

C8H20Cl2N4O2

Molecular Weight

275.18

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]Latika Sibal, et al. The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease. Curr Cardiol Rev. 2010 May;6 (2) :82-90.