L-Cysteine S-sulfate

L-Cysteine S-sulfate is a potent N-methyl-d-aspartate (NMDA) glutamatergic receptor agonist. L-Cysteine S-sulfate is the substrate for cystine lyase, and can be used in mass spectrometry operations[1][2][3].

Product Specifications

CAS Number

[1637-71-4]

UNSPSC

12352209

Hazard Statement

H315-H319-H335

Target

Endogenous Metabolite; iGluR

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-cysteine-s-sulfate.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](CSS(=O)(O)=O)C(O)=O

Molecular Formula

C3H7NO5S2

Molecular Weight

201.22

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Steventon GB, et, al. Comparison of the sulfur-oxygenation of cysteine and S-carboxymethyl-l-cysteine in human hepatic cytosol and the rôle of cysteine dioxygenase. J Pharm Pharmacol. 2018 Aug;70 (8) :1069-1077.|[2]Macaluso V, et al. l-Cysteine Modified by S-Sulfation: Consequence on Fragmentation Processes Elucidated by Tandem Mass Spectrometry and Chemical Dynamics Simulations. J Phys Chem A. 2019 May 2;123 (17) :3685-3696.|[3]Elucidated by Tandem Mass Spectrometry and Chemical Dynamics Simulations. J Phys Chem A. 2019 May 2;123 (17) :3685-3696.