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Thiamine pyrophosphate-d3

Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

Product Specifications

CAS Number

[2483831-79-2]

UNSPSC

12352005

Hazard Statement

H317

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

97.39

Solubility

10 mM in DMSO

Smiles

CC([N+](CC1=CN=C(C([2H])([2H])[2H])N=C1N)=CS2)=C2CCOP(OP(O)(O)=O)(O)=O.[Cl-]

Molecular Formula

C12H16D3ClN4O7P2S

Molecular Weight

463.79

Precautions

H317

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

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