Thiamine pyrophosphate-d3
Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Product Specifications
CAS Number
[2483831-79-2]
UNSPSC
12352005
Hazard Statement
H317
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
97.39
Solubility
10 mM in DMSO
Smiles
CC([N+](CC1=CN=C(C([2H])([2H])[2H])N=C1N)=CS2)=C2CCOP(OP(O)(O)=O)(O)=O.[Cl-]
Molecular Formula
C12H16D3ClN4O7P2S
Molecular Weight
463.79
Precautions
H317
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113076S/Thiamine-pyrophosphate-d3-SDS-MedChemExpress.pdf
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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