Guanosine 5'-diphosphate-15N5 (dilithium)
Guanosine 5'-diphosphate-15N5 (GDP-15N5) dilithium is 15N labeled Guanosine 5'-diphosphate. Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6) /stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI)[2][3].
Product Specifications
Product Name Alternative
GDP-15N5 (dilithium)
UNSPSC
12352005
Target
Endogenous Metabolite; Hepcidin; Isotope-Labeled Compounds; Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Concentration
100 mM in 21.74 μL Tris HCl/H2O buffer pH=7.5
Purity
98.20
Solubility
10 mM in DMSO
Smiles
O=P(OP(O[Li])(O[Li])=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H]([15N]2C([15N]=C([15NH2])[15NH]C3=O)=C3[15N]=C2)O1
Molecular Formula
C10H13Li2 15N5O11P2
Molecular Weight
460.03
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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